Table 2.
Hydrogel summary: physicochemical, in vitro, and in vivo properties.
| Properties | AdipoGel | Cellulose | ObaGel | |
|---|---|---|---|---|
| Physicochemical | Source | Adipose | Plant | Blood |
| Enriched proteins or polymers | ECM | Cellulose | Angio/Coag | |
| Chemical modifiability | ++ | ++ | ++ | |
| Potential stability at room temperature | ++ | +++ | ++ | |
| In vitro | Stromal-cell-compatible | ASC | TBD | ASC |
| ASC differentiation | Adipogenic and osteogenic | TBD | Adipogenic and endothelial | |
| In vivo | Angiogenic | + | TBD | +++ |
| Soft tissue regeneration | ++ | TBD | + | |
| Hemostatic | TBD | ++ | TBD | |
| Antimicrobial | TBD | +++ | TBD | |
| Potential for synergy in combination | +++ | +++ | +++ | |
Abbreviations: Angio, Angiogenic; ASC, Adipose Stromal/Stem Cells; Coag, Coagulation; ECM, Extracellular Matrix; TBD, To Be Determined. + = strong, ++ =stronger, +++ =strongest