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. 2020 Sep 26;9(10):2175. doi: 10.3390/cells9102175

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Common upstream regulators altered (activated/inhibited) in transcriptome and proteome. Targets identified in LECs transfected with miR-146aM vs. MC in transcriptome (A) and in proteome (B). Notch signaling regulators are listed in bold. The activation or inhibition is estimated by a Z-score, which represents the number of standard deviations that a value is away from the mean of a gene value in all the sample groups. Genes that are differentially expressed in our dataset are indicated as fold change in red.