Table 3.
Quantification of ammonium stress-test data of five independent experiments (donors).
| AST Characteristics | Control | t-BOOH | A23187 | SNC | |||
|---|---|---|---|---|---|---|---|
| 0.5 mM | 1 mM | 1.5 mM | 2 mM | 1 µM | 500 µM | ||
| Vhem | 1.00 ± 0.02 | 1.01 ± 0.02 | 0.71 ± 0.21 | 0.57 ± 0.08 * | 0.32 ± 0.09 * | 0.06 ± 0.02 ** | 1.04 ± 0.02 |
| %Hem | 96.5 ± 0.2 | 92.1 ± 2.6 | 80.8 ± 11.4 | 69.3 ± 9.6 * | 47.8 ± 13.2 ** | 40.0 ± 11.3 ** | 95.6 ± 1.0 |
| MCV300 | 84.9 ± 0.9 | 86.7 ± 2.3 | 87.5 ± 5.9 | 87.8 ± 4.3 | 88.6 ± 10.4 | 70.5 ± 3.7 * | 86.87 ± 1.9 |
| MCVhem | 142.3 ± 3.2 | 143.8 ± 4.8 | 124.5 ± 9.8 | 116.0 ± 1.7 * | 105.1 ± 1.9 ** | 96.3 ± 6.5 ** | 141.0 ± 2.8 |
MCV300—data from hematology cell counter. Data are presented as means ± SD (n = 5), one-way ANOVA; if Levene’s test < 0.05, Tamhane T2 post hoc (Vhem, MCV300, MCV120) was used, if Levene’s test > 0.05, Tukey HSD post hoc (%Hem) was used. * p < 0.05, ** p < 0.001, compared to corresponding control.