Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 15;12(10):976. doi: 10.3390/pharmaceutics12100976

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

(A) Mechanism of lyophilizate for dry powder inhalation (LDPI) system. (1) Air is introduced into the vial in synchronization with the patient’s inhalation through the two-way needle device. (2) Lyophilizate with a porous matrix structure is broken into pieces by air impact and aerosolized by the convection flow of air in the vial. (3) Porous particles reconstructed from pieces of lyophilizate are emitted through the device. (B) Enlarged picture of LDPI formulation and scanning electron microscope image. LDPI formulation is a lyophilized cake having porous matrix with fiber-like network structure.