Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibitors of UEV domains.
| Peptide Inhibitors [10] | Experimental Binding Free Energies Values (ΔGexp)(kcal/mol) | |
|---|---|---|
| Native | Pro-Glu-Pro-Thr-Ala-Pro-Pro-Glu-Glu | −6.05 (IC50 = 54.0 uM), |
| CP1 | Cyclo-(Ser-Gly-Trp-Ile-Tyr-Trp-Asn-Val) | −6.11 (IC50 = 48.6 uM), |
| CP2 | Cyclo-(Ser-Gly-Trp-Ile-Ala-Trp-Asn-Val) | −5.00 (IC50 = 296.3 uM), |
| CP3 | Cyclo-(Ser-Gly-Trp-Ile-Tyr-Trp-Ala-Val) | −6.50 (IC50 = 25.8 uM), |
ΔGexp: experimental free energies (kcal/mol).
