Table 5.

Information of SIE free energy calculations for UEV domain protein.

Cyclic Peptides	CP1	CP2	CP3
Inter vdW	−32.54 ± 0.41	−28.16 ± 0.17	−31.42 ± 0.42
Inter Coulomb	−41.37 ± 0.15	−38.45 ± 0.23	−45.94 ± 0.13
Reaction Field	64.32 ± 0.81	62.11 ± 0.15	62.54 ± 0.26
Cavity	−20.68 ± 0.17	−18.64 ± 0.13	−19.85 ± 0.19
Constant	−2.89	−2.89	−2.89
△GBinding (kcal/mol)	−6.05 ± 0.14	−5.31 ± 0.16	−6.52 ± 0.11