Table 1.
Baseline demographic characteristics and underlying comorbidities in acute HEV-infected patients by HEV GT3 subtype.
| Characteristics | HEV GT3 | HEV GT3c | HEV GT3e | HEV GT3f | p-Value |
|---|---|---|---|---|---|
| (n = 37) | (n = 6) | (n = 8) | (n = 21) | ||
| Age, years median (IQR) | 59 (52–68) | 59.5 (51.5–63) | 59 (49–66) | 65 (53–71) | 0.2 |
| Male sex (n, %) | 32 (86.5%) | 6 (100%) | 7 (87.5%) | 17 (80.9%) | 0.2 |
| BMI, kg/m2 | 24.66 ± 3.13 | 27.9 ± 4.9 | 24.6 ± 2.9 | 24.0 ± 2.9 | 0.6 |
| Alcohol user, (n, %) | 11/27 (40.7%) | 1/2 (50%) | 1/7 (14.3%) | 7/17 (41.2%) | 0.4 |
| Smoker, (n, %) | 8/26 (30.8%) | 1/2 (50%) | 1/6 (16.7%) | 5/16 (31.2%) | 0.6 |
| PWID, (n, %) | 2/37 (5.4%) | 0 | 0 | 2/21 (9.5%) | 0.9 |
| Chronic liver disease, (n, %) | 3/37 (8.1%) | 1 (16.7%) | 0 | 2 (9.5%) | 0.9 |
| Number of comorbidities | |||||
| 0 | 10 (27%) | 1 (16.7%) | 4 (50%) | 3 (14.2%) | |
| 1 | 15 (40.5%) | 2 (33.3%) | 2 (25%) | 11 (52.4%) | |
| 2 | 2 (5.4%) | 1 (16.7%) | 0 | 1 (4.7%) | |
| 3 | 7 (18.9%) | 2 (33.3%) | 2 (25%) | 3 (14.3%) | |
| 4 | 1 (2.7%) | 0 | 0 | 1 (4.7%) | |
| 5 | 2 (5.4%) | 0 | 0 | 2 (9.5%) | |
| Diabetes, (n, %) | 13 (35.1%) | 3 (50%) | 2 (25%) | 8 (38.1%) | 0.6 |
| Cardiovascular diseases, (n, %) | 8 (21.6%) | 1 (16.7%) | 1 (12.5%) | 6 (28.6%) | 0.6 |
| Lipid disorders, (n, %) | 7 (18.9%) | 1 (16.7%) | 1 (12.5%) | 5 (23.8%) | 0.7 |
| Renal diseases, (n, %) | 1 (2.7%) | 0 | 0 | 1 (4.8%) | |
| Arterial hypertension, (n, %) | 17 (45.9%) | 4 (66.7%) | 3 (37.5%) | 10 (47.6%) | 0.5 |
| Digestive diseases, (n, %) | 3 (8.1%) | 0 | 0 | 3 (14.3%) | 0.9 |
| Respiratory diseases, (n, %) | 3 (8.1%) | 1 (16.7%) | 1 (12.5%) | 1 (4.8%) | 0.6 |
| Neoplastic diseases, (n, %) | 2 (5.4%) | 0 | 0 | 2 (9.5%) | 0.9 |
Interquartile range, IQR; body mass index, BMI; people who inject drugs, PWID.