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. 2020 Nov 4;13:2805–2814. doi: 10.2147/JPR.S262390

Table 2.

Ratios (95% CIs) of Adjusted Geometric Means of Cumulative Absorption at 24h for Diclofenac and Ibuprofen Formulations

Diclofenac Formulations
vs Diclo-1 vs Diclo-2 vs Diclo-3 vs Diclo-4 vs Diclo-5 vs Diclo-6
Diclo-1 4.06 (2.54–6.50) 2.54 (1.59–4.07) 3.67 (2.29–5.88) 7.13 (4.46–11.42) 1.14 (0.71–1.82)
Diclo-2 0.25 (0.15–0.39) 0.63 (0.39–1.00) 0.91 (0.57–1.45) 1.76 (1.10–2.81) 0.28 (0.18–0.45)
Diclo-3 0.39 (0.25–0.63) 1.60 (1.00–2.55) 1.44 (0.90–2.31) 2.80 (1.75–4.49) 0.45 (0.28–0.72)
Diclo-4 0.27 (0.17–0.44) 1.10 (0.69–1.77) 0.69 (0.43–1.11) 1.94 (1.21–3.11) 0.31 (0.19–0.50)
Diclo-5 0.14 (0.09–0.22) 0.57 (0.36–0.91) 0.36 (0.22–0.57) 0.51 (0.32–0.82) 0.16 (0.10–0.26)
Diclo-6 0.88 (0.55–1.41) 3.57 (2.23–5.71) 2.24 (1.40–3.58) 3.23 (2.02–5.17) 6.27 (3.92–10.04)
Ibuprofen Formulations
vs Ibu-1 vs Ibu-2 vs Ibu-3 vs Ibu-4 vs Ibu-5 vs Ibu-6
Ibu-1 1.11 (0.85–1.45) 1.44 (1.10–1.88) 1.56 (1.20–2.04) 0.60 (0.46–0.79) 0.37 (0.28–0.48)
Ibu-2 0.90 (0.69–1.17) 1.29 (0.99–1.69) 1.40 (1.08–1.83) 0.54 (0.42–0.71) 0.33 (0.25–0.43)
Ibu-3 0.69 (0.53–0.91) 0.77 (0.59–1.01) 1.09 (0.83–1.42) 0.42 (0.32–0.55) 0.26 (0.20–0.33)
Ibu-4 0.64 (0.49–0.83) 0.71 (0.55–0.93) 0.92 (0.71–1.20) 0.39 (0.30–0.50) 0.24 (0.18–0.31)
Ibu-5 1.66 (1.27–2.16) 1.85 (1.42–2.41) 2.39 (1.83–3.12) 2.59 (1.99–3.38) 0.61 (0.47–0.80)
Ibu-6 2.72 (2.09–3.55) 3.03 (2.32–3.95) 3.92 (3.01–5.11) 4.25 (3.26–5.55) 1.64 (1.26–2.14)