Figure 1.

Distribution of differentially expressed genes in yeast cells grown with and without melatonin (5 μM or 25 μM), in stressed (2 mM of H₂O₂) and in unstressed conditions (Control, Mel, MelH, 25MelH and H). (A) The number of differentially expressed genes between different conditions (fold change −1 ≤ FC ≥ 1; p-value < 0.05). (B,C) Venn diagram showing the number of common genes found among the Mel vs. Control, MelH vs. Control and H vs. Control comparisons (up- (B) and down (C) regulated genes). (D) Venn diagram showing the number of common genes found among the up- and downregulated genes identified in the Mel vs. Control and MelH vs. H comparisons. (E) List of genes in some groups indicated in (B–D). The list of genes and the GO enrichment analysis of all the groups is shown in Table S1.