Table 3.

Anti-infective Treatment Durations of Study Patients Before Skin Evaluation According to Skin Manifestations

Type of Cutaneous Manifestation	No. of Patients With at Least 1 Anti-infective Treatment (n = 23)	Treatment Duration Before Skin Evaluation, d
		HCQ (n = 6)	Beta-lactam (AMX or CRO) (n = 4)	AZM (n = 2)	HCQ + AZM (n = 7)	SP + CRO (n = 2)	HCQ + AZM + Beta-lactam (n = 2)
Macular exanthema (n = 32)	19	n = 4	n = 4	n = 2	n = 5	n = 2	n = 2
		•P2: 7 •P5: 6 •P7: 6 •P11: 7	•P4: 13 •P8: 1 •P12: 3 •P24: 1	•P21: 3 •P32: 3	•P3: 5 •P13: 5 •P17: HCQ (6) + AZM (5) •P22: 8 •P27: 1	•P25: 1 •P34: 1	•P1: HCQ (5) + AZM (5) + CRO (4) •P14: HCQ (5) + AZM (5) + AMX (2)
Maculo-papular exanthema (n = 3)	1	-	-	-	n = 1	-	-
					P19: 5
Urticarial rashes (n = 3)	1	-	-	-	n = 1	-	-
					P22: 8
Face edema (n = 13)	8	n = 1	n = 2	n = 1	n = 2	-	n = 2
		P23: 6	•P8: 1 •P24: 1	P21: 3	•P13: 5 •P19: 5		•P1: 5 •P14: 5
Livedo reticularis (n = 5)	3	-	n = 1	-	n = 2	-	-
			P24: 1		•P17: HCQ 6 + AZM 5 •P22: 8
Purpura (n = 2)	1	-	-	-	-	-	n = 1
							P14: 5
Exacerbation of atopic dermatitis (n = 1)	1	n = 1	-	-	-	-	-
		P23: 6
Oral lichenod reaction (n = 13)	9	n = 2	n = 2	-	n = 5	-	-
		•P5: 6 •P28: 4	•P12: 3 •P24: 1		•P3: 5 •P17: HCQ 6 + AZM 5 •P19: 5 •P22: 8 •P27: 1
Macroglossia (n = 10)	8	-	n = 1	n = 1	n = 5	-	n = 1
			P12: 3	P21: 3	•P3: 5 •P13: 5 •P16: HCQ 3 + AZM 4 •P19: 5 •P22: 8		P1: 5
Herpes (n = 1)	0	-	-	-	-	-	-
Enanthema (n = 11)	9	n = 1	n = 3	n = 1	n = 3	-	n = 1
		P5: 6	•P8: 1 •P12: 3 •P24: 1	P21: 3	•P19: 5 •P22: 8 •P27: 1		P1: 5
Cheilitis (n = 6)	2	-	-	-	n = 2	-	-
					•P19: 5 •P27: 1
Conjonctivitis (n = 7)	4	-	n = 1	-	n = 2	-	n = 1
			P24: 1		•P19: 5 •P22: 8		P1: 5

Abbreviations: AMX, amoxicillin; AZM, azithromycin; CRO, ceftriaxone; HCQ, hydroxychloroquin; P, patient; SP, spiramycin.