Table 4. .

Confirmed Cases of CIED Infection

Age, Race/Sex	Device	Arrhythmia and EF	Risk Factors	Cancer	Oncologic Therapy (Pre-CIED)	Oncologic Therapy (Post-CIED)	Laboratory Values (ANC/platelets)	IV Access	Antimicrobials to Prevent CIED Infection	Non-CIED Infection	CIED Infection and Management (Time From CIED Placement)
48 y, WM	PPM	Atrial flutter, third-degree heart block, 50%	2 leads, oral antiplatelets, anticoagulation, PPM for 5 y prior, and CIED endocarditis	Hodgkin lymphoma	Mantle cell radiation, chemotherapy, splenectomy, and autologous HSCT	None	5180 cells/μl352 cells/μl	PICC	(a) Preoperative vancomycin, (b) polymyxin B plus bacitracin pocket irrigation, (c) resorbable TYRX, (d) postoperative minocycline	Septic shock, pneumonia, and pneumococcal bacteremia	Lead infection (pneumococcus) status post–PPM exchange and 6 wk of antimicrobials (118 d)
74 y, WF	CRT-D	Atrial fibrillation, 25% (chemotherapy-induced cardiomyopathy)	HTN, CAD, 3 leads, oral anticoagulation, ICD for 2 y prior	Invasive ductal breast carcinoma	Bilateral mastectomy, chest radiation, chemotherapy, and hormonal therapy	Chest radiation and hormonal therapy	800 cells/μl224 cells/μl	None	(a) Preoperative vancomycin, (b) polymyxin B plus bacitracin pocket irrigation, (c) resorbable TYRX, (d) postoperative minocycline	Recurrent urinary tract infections	Generator infection (culture negative) status post CRT-D exchange and 2 weeks of antimicrobials (1174d)

Abbreviations: ANC, absolute neutrophil count; CAD, coronary artery disease, CRT-D, cardiac resynchronization therapy defibrillator; EF, ejection fraction; HSCT, hematopoietic stem cell transplantation; HTN, hypertension; ICD, implantable cardio defibrillator; IV, intravenous; PICC, peripherally inserted central catheter; PPM, permanent pacemaker; W, White.