Table 8.
Nasal shedding following PI3V challenge
| PI3V | PI3V titres in nasal swabs (log TCID50): control animals Days post PI3V challenge |
Days of shedding | Total nasal viral shedding (TCID50) | ||||||||||
| Animal ID | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 → 14 | ||
| 632181 | 2.1 | 2.1 | 2.6 | 4.8 | 6.6 | 6.1 | 4.3 | 2.3 | 2.1 | 2.1 | ← 2.1 → | 6 | 26.7 |
| 643429 | 2.1 | 2.1 | 2.3 | 5.3 | 5.1 | 7.3 | 3.6 | 3.3 | 2.8 | 2.1 | 7 | 29.7 | |
| 643433 | 2.1 | 2.3 | 5.8 | 7.6 | 6.3 | 7.3 | 5.8 | 3.1 | 2.3 | 2.3 | 8 | 40.5 | |
| 689106 | 2.1 | 2.1 | 2.1 | 5.6 | 5.3 | 7.3 | 5.3 | 2.8 | 2.3 | 2.1 | 6 | 28.6 | |
| 689109 | 2.1 | 3.3 | 2.6 | 3.8 | 4.6 | 4.8 | 2.3 | 2.1 | 2.1 | 2.1 | 6 | 21.4 | |
| PI3V titres in nasal swabs (log TCID50): vaccinated MDA− animals Days post PI3V challenge |
|||||||||||||
| 637676 | ← 2.1 → | 0 | 0 | ||||||||||
| 643435 | 0 | 0 | |||||||||||
| 643436 | 0 | 0 | |||||||||||
| 643437 | 0 | 0 | |||||||||||
| 643439 | 0 | 0 | |||||||||||
| 643440 | 0 | 0 | |||||||||||
| PI3V titres in nasal swabs (log TCID50): vaccinated MDA+ animals Days post PI3V challenge |
|||||||||||||
| 643425 | 2.1 | 3.1 | ← 2.1 → | 1 | 3.1 | ||||||||
| 643426 | ← 2.1 → | 0 | 0 | ||||||||||
| 643428 | 0 | 0 | |||||||||||
| 643430 | 0 | 0 | |||||||||||
| 643431 | 0 | 0 | |||||||||||
| 689107 | 0 | 0 | |||||||||||
PI3V titres ≤2.1 considered negative.
MDA, maternally derived antibodies; PI3V, parainfluenza type 3 virus.