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. 2020 Oct 22;20(6):240. doi: 10.3892/etm.2020.9370

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Paroxetine combined with fluorouracil inhibits xenograft tumor growth in mice. Tumor-bearing mice were used to detect tumor growth in each group. (A) The dynamic growth curve of tumor volume. ^*P<0.05 compared to the CD group. ^#P<0.05 compared to the CDP group. ^ΔP<0.05 compared to the CDF group. (B) The tumor weight of the various groups on the 42nd day. (C) The inhibition rate of tumors. ^*P<0.05. (D) Photos of tumor xenografts. CA, cancer model group; CD, cancer depression model group; CDP, cancer depression with paroxetine group; CDF, cancer depression with fluorouracil group; CDP+F, cancer depression with paroxetine and fluorouracil group.