Table 6. Pharmacokinetic profile of compounds 48 and 50 in Balb-c mice, dosed orally.
Compound | Dose mg kg–1 | AUC ng min ml–1 | C max ng ml–1 | T max h |
48 | 100 | 1 253 767 | 5765 | 1 |
50 | 100 | 2 388 964 | 5229 | 4 |
Compound | Dose mg kg–1 | AUC ng min ml–1 | C max ng ml–1 | T max h |
48 | 100 | 1 253 767 | 5765 | 1 |
50 | 100 | 2 388 964 | 5229 | 4 |