Table 8. Rat PK data for 48 at 10, 100 and 300 mg kg–1.
Dose (mg kg–1) | C max (ng ml–1) | T max (h) | AUC (0-Tlast) (ng h ml–1) |
10 | 229 | 0.67 | 488 |
100 | 5520 | 6.00 | 50621 |
300 | 6760 | 6.67 | 84647 |
Dose (mg kg–1) | C max (ng ml–1) | T max (h) | AUC (0-Tlast) (ng h ml–1) |
10 | 229 | 0.67 | 488 |
100 | 5520 | 6.00 | 50621 |
300 | 6760 | 6.67 | 84647 |