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. 2017 Jan 13;24(4):697–708. doi: 10.1093/jamia/ocw168

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© The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. For Permissions, please email: journals.permissions@oup.com

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Figure 3. — Evaluation of the ROC curves of pharmacovigilance algorithms created by (A) MetaLAB ( ${ML}_{L}^{RS}$ , AUCs = 0.69 ± 0.11) and (B) MetaNurse ( ${MN}_{N}^{RS}$ , AUCs = 0.62 ± 0.07) against the extensive RS-ADR gold standard comprising 117 and 757 MedDRA PTs, respectively, for 101 precautionary drugs. ROC curves for the 10 drugs reported by Yoon et al.¹³ for MetaLAB analysis against 11 817 drug-ADR pairs are presented as colored curves.