Table 4. Selectivity index for benzoates-TPP+ derivatives at 48 h values were calculated from IC50 ratio between non-tumor cell and tumor cell lines from the respective sigmoidal dose–response curves.
| Compounds | Selectivity index (48 h) |
||
| OKF-6 TERT/Cal-27 | OKF-6 TERT/HEp-2 | OKF-6 TERT/SCC-15 | |
| SA-TPP + C 10 (5be) | 5.5 | 3.0 | 4.0 |
| GA-TPP + C 10 (5bd) | 6.0 | 2.3 | 4.9 |
| PIA-TPP + C 10 (5bb) | 4.7 | 0.9 | 2.6 |
| TPP + C 10 (5ba) | 3.8 | 1.0 | 4.4 |
| Cisplatin (CDDP) | <1.0 | <1.0 | <1.0 |