Skip to main content
. 2020 Aug 19;11(10):1210–1225. doi: 10.1039/d0md00153h

Table 4. Selectivity index for benzoates-TPP+ derivatives at 48 h values were calculated from IC50 ratio between non-tumor cell and tumor cell lines from the respective sigmoidal dose–response curves.

Compounds Selectivity index (48 h)
OKF-6 TERT/Cal-27 OKF-6 TERT/HEp-2 OKF-6 TERT/SCC-15
SA-TPP + C 10 (5be) 5.5 3.0 4.0
GA-TPP + C 10 (5bd) 6.0 2.3 4.9
PIA-TPP + C 10 (5bb) 4.7 0.9 2.6
TPP + C 10 (5ba) 3.8 1.0 4.4
Cisplatin (CDDP) <1.0 <1.0 <1.0