AJCC eighth edition pathological prognostic groups (TNM) for stage I to IV cutaneous melanoma. T0 – no evidence of primary tumor (e.g. unknown primary or completely regressed melanoma); Tis – melanoma in situ; TX – thickness cannot be assessed; NX – Regional nodes not assessed (e.g. SLN biopsy not performed, regional nodes previously removed for another reason). Exception: pathological N category is not required for T1 melanoma, use cN. *Pathological stage is IV for Any T, any N and M1 disease. aAdapted and used with permission from Gershenwald JE, Scolyer RA, Hess KR, Sondak VK, et al. Melanoma staging: evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual. CA Cancer J Clin. 2017; 67:472–491.