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. 2020 Oct 15;31(3):145–159. doi: 10.21315/tlsr2020.31.3.10

Table 3.

The efficacy of Cassia siamea extracts against the motility of C. elegans Bristol N2 and C. elegans DA1316 L4 larvae.

Concentration (mg mL−1) C. elegans Bristol N2 C. elegans DA1316

Time/hour

24 48 24 48
Aqueous extract
0.2 91.8 ± 0.58 81.0 ± 0.58 93.8 ± 0.58 84.2 ± 0.56
0.4 87.9 ± 0.65 78.2 ± 0.58 90.9 ± 0.70 81.2 ± 0.47
0.6 84.6 ± 0.88 73.1 ± 0.72 88.2 ± 0.58 75.2 ± 0.55
0.8 80.6 ± 0.87 65.2 ± 0.55 84.2 ± 0.53 69.2 ± 0.58
1.0 77.1 ± 0.60 56.2 ± 0.58 79.3 ± 0.54 62.2 ± 0.55
2.0 69.5 ± 0.67 30.6 ± 0.68 74.8 ± 0.60 33.9 ± 0.67
Ivermectin 36.5 ± 0.89 2.33 ± 0.47 98.5 ± 0.27 96.4 ± 0.29
M9 solution 97.9 ± 0.28 96.3 ± 0.71 98.3 ± 0.74 97.2 ± 0.03

Methanol extract
0.2 81.4 ± 0.58 72.6 ± 0.58 83.6 ± 0.58 73.9 ± 0.35
0.4 77.4 ± 0.58 67.5 ± 0.65 79.2 ± 0.57 67.9 ± 0.67
0.6 74.2 ± 0.61 62.9 ± 0.73 75.9 ± 0.65 64.2 ± 0.61
0.8 71.3 ± 0.58 45.2 ± 0.61 70.6 ± 0.63 55.3 ± 0.55
1.0 65.9 ± 0.65 30.8 ± 0.65 67.2 ± 0.61 43.2 ± 0.51
2.0 53.9 ± 0.65 13.3 ± 0.98 58.1 ± 0.57 15.1 ± 0.73
Ivermectin 37.2 ± 0.61 2.67 ± 0.72 98.3 ± 0.58 95.8 ± 0.26
M9 solution 98.0 ± 0.45 96.1 ± 0.35 97.1 ± 0.82 96.1 ± 0.32

Notes: Data are presented as a percentage means ± standard error for 3 independent experiments. L4 larvae of C. elegans Bristol N2 and DA1316 were incubated for 48 h in different concentration of the extracts (0.2, 0.4, 0.6, 0.8, 1.0 and 2.0 mg mL−1). Counting of the immotile worms was carried out after 24 h and 48 h.