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. 2020 Nov 9;15(11):e0242152. doi: 10.1371/journal.pone.0242152

Table 1. Characteristics of older adults according to SEGAm score.

Characteristic Non-frail n = 50 Frail n = 40 Very-frail n = 51 p value
Assessment of general data
Age, years, median (range) 69 (66–72.25) 77 (71–81.75) 80 (73–85) <0.001
Age ≥ 80 years, n (%) 4 (8) 15 (37.5) 26 (51) <0.001
Gender: female/male, n (%) 15/35 19/21 27/24 0.054
BMI, kg/m2, mean ± SD 26.11 ± 4.71 a 25.92 ± 4.92 a 23.27 ± 4.59 b 0.014
Assessment of living condition <0.001
With spouse, n (%) 30 (60) 6 (15) 9 (17.6)
With children, n (%) 12 (24) 9 (22.5) 12 (23.5)
Nursing home, n (%) 8 (16) 25 (62.5) 30 (59)
Assessment of general health status
Diabetes, n (%) 24 (48) 10 (25) 17 (33.3) 0.068
Hypertension, n (%) 22 (44) 20 (50) 30 (58.8) 0.325
Dyslipoproteinemia, n (%) 7 (14) 5 (12.5) 5 (9.8) 0.807
Other, n (%) 32 (64) 28 (70) 43 (84.3) 0.062
Polypharmacy ≥ 3 n (%) 30 (60) 23 (57.5) 35 (69) 0.503
Assessment of cognitive status and mood
Mini-Cog score, median (range) 4 (3–5) 2 (2–3) 1 (0–2) <0.001
Mini-GDS score, median (range) 0 (0–1) 3 (1–4) 4 (4–4) <0.001
Mini-GDS ≥ 1, n (%) 18 (36) 33 (82.5) 46 (90.2) <0.001
Assessment of nutritional status
MNA-SF score, median (range) 12 (10–14) 8.5 (7–10) 5 (4–7) <0.001
MNA-SF at risk of malnutrition ≤ 8, n (%) 2(4) 12 (30) 44 (86.3) <0.001
Assessment of living independence
ADL score, median (range) 6 (3.5–6) 4.5 (3.6–5.5) 2 (0–4.5) <0.001
ADL ≤ 5, n (%) 8 (16) 22 (55) 49 (96) <0.001
Assessment of physical performance
Timing TUG, seconds, median (range) 17.23 (13.76–20.46) 27.41 (18.23–29.73) 28.49 (20.81–31.52) <0.001
Assessment of biochemical data
Glycemia, mmol/l, median (range) 7.3 (5.8–10.2) 5.9 (4.9–6.55) 5.5 (4.6–7.8) 0.014
HbA1c, %, median (range) 7.7 (6.8–8.6) 6.4 (5.7–8) 6.9 (6.1–9.32) 0.36
Albumin, g/l, mean ± SD 36.30 ± 6.16 a,b 39.81 ± 4.69 a 33.65 ± 9.66 b 0.006

a, b Different superscript letters in the same row indicate significant difference between values at p<0.05 (Duncan’s multiple range test).

BMI, Body mass index; Mini-Cog, Mini Cognitive; Mini-GDS, Mini Geriatric Depression Scale; MNA-SF Mini Nutritional Assessment Short-Form ADL, Activities of Daily Living; TUG, Timed Up and Go; HbA1c, hemoglobin A1c.