Table 2. Univariate and multivariate analysis of prognostic factors for OS (CI: confidence interval; HR: hazard ratio; Nº: number).
| Prognostic factors for OS | ||||
|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | |||
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age | 1.01 (0.99–1.03) | p = 0.411 | ||
| Gender (male) | 1.22 (0.75–1.97) | p = 0.423 | ||
| Lymphovascular invasion | 1.54 (0.67–3.56) | p = 0.315 | ||
| Perineural invasion | 1.30 (0.74–2.27) | p = 0.367 | ||
| Size of tumour (≥4.5 cm) | 1.18 (0.69–2.04) | p = 0.549 | ||
| Type of lymph node dissection D1 D1+ D2 |
1 0.32 (0.10–1.07) 0.36 (0.11–1.21) |
p = 0.179 |
||
| Nº of lymph nodes removed (≥30) | 0.88 (0.55–1.42) | p = 0.598 | ||
| Extracapsular extension | 1.96 (1.11–3.45) | p = 0.020 | 1.84 (1.02–3.32) | p = 0.033 |
| T T2 T3 T4a T4b |
1 1.04 (0.25–4.35) 1.70 (0.41–7.11) 1.08 (0.10–5.93) |
p = 0.236 |
||
|
N N0 N1 N2 N3a N3b |
1 2.95 (0.38–23.28) 1.70 (0.22–13.33) 2.29 (0.31–17.09) 5.52 (0.72–42.13) |
p = 0.007 |
1 2.08 (0.25–17.02) 0.86 (0.10–7.22) 0.88 (0.10–7.48) 1.33 (0.13–13.37) |
p = 0.024 |