Figure 2. Deletion of TRPV1 exacerbates WD-induced renal collagen deposition. (A) The amount of hydroxyproline per milligram of dry kidney tissue in WT and TRPV1–/– mice fed normal (CON) or western diet (WD). Values are mean±SEM (n=6). (B) Periodic acid–Schiff (PAS)-stained glomeruli. Magnification: 400×. *p<0.05 vs. WT-CON; †p<0.05 vs. TRPV1–/–-CON; ‡p<0.05 vs. WT-WD.
