Figure 3. Deletion of TRPV1 exacerbates WD-induced renal macrophage infiltrations. (A) Immunostaining of F4/80-positive cells (macrophages in red) in the kidney from WT and TRPV1–/– mice with normal diet (CON) or western diet (WD) intake for 23 weeks. Arrows: F4/80-positive cells. Magnification: 400×. (B) Quantification of macrophages was expressed as cells per square millimeter. Values are mean±SEM (n=4-5). *p<0.05 vs. WT-CON; †p<0.05 vs. TRPV1–/–-CON; ‡p<0.05 vs. WT-WD.
