Table 4.
Sex differences in cardiac damage in patients with severe type of COVID-19
| Median (IQR) or N (%) | p Value a | ||
|---|---|---|---|
| Men (n = 56) | Women (n = 44) | ||
| Age ≥ 60 y | 31 (55.4) | 29 (65.9) | 0.285 |
| Comorbidities | 34 (60.7) | 35 (79.5) | 0.043 |
| Hypertension | 18 (32.1) | 22 (50.0) | 0.070 |
| Diabetes | 9 (16.1) | 12 (27.3) | 0.172 |
| CVD | 5 (8.9) | 10 (22.7) | 0.055 |
| Hyperlipidemia | 1 (1.8) | 1 (2.3) | 1.000 |
| Cardiac damage | 18 (32.1) | 7 (15.9) | 0.063 |
| hsTnI, pg/ml | 4.2 (1.9–12.8) | 2.9 (1.9–7.4) | 0.018 |
| Increased (> 34.2) | 5 (10.4) | 5 (11.6) | 0.340 |
| NTproBNP, pg/ml | 272.5 (57.0–559.8) | 86.0 (31.3–209.3) | 0.013 |
| Increased# | 18 (32.1) | 4 (9.1) | 0.006 |
ap < .05 was considered statistically significant. COVID-19 = coronavirus disease 2019; CVD = cardiovascular disease; hsTnI = hypersensitive troponin I; NTproBNP = N-terminal-pro brain natriuretic peptide. #Increased NTproBNP was above 450 pg/ml at the age < 50, above 900 pg/ml at the age < 75, or above 1800 pg/ml at the age ≥ 75