Figure 4.

The COG function differences of oral bacteria among the PC, BPD, and HC groups. Statistical significance between groups was calculated by the K-W test and post hoc Dunn's test. (a) For the total twenty-five COG terms, the bar plot depicted the relative changes among the three groups based on the sequence number, and the dot plot exhibited the statistical significance between groups. (b) Box plots showed four COG functions apparently changed between PC and HC groups, which are observably or proven associated with pancreatic cancer. The symbol of “∗” indicates that P value is less than 0.05.