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. 2020 Oct 27;11:596324. doi: 10.3389/fendo.2020.596324

Table 2.

Summary of human endometrial stromal cell studies included.

Author, year Sample size (fertility) Cycle stage Relevant results
Gililland et al., 1992 (47) n = 7 (fertile) Endometrial tissue (P n = 2; ES n = 3, LS n = 2) Specific high affinity ANP-R were identified in endometrial tissue, and may regulate cell function or development via cGMP
Schumann et al., 2015 (48) Decidua, n = 4;
Endometrial tissue: n = 6 (fertile)
Decidua (7–9 weeks pregnant);
Endometrial tissue (P n = 3, S n = 3)
Claudin-3 and -10 were identified in the endometrial epithelium but not early pregnancy decidua, and claudin-3 in extravillous trophoblast
Murakami et al., 2014 (49) n = 43 (unknown) Endometrial tissue (6–10 days post-LH surge) SUSD2 expression alters with cell-cell contact and Notch signalling, and thus alters the perivascular secretome upon decidualization
Szwarc et al., 2018 (50) Unknown (unknown) Endometrial tissue (all P) A subset of stromal cell genes regulated by PGR during decidualization also requires SRC-2, for example retinoid signaling

P, proliferative; ES, early-secretory; LS, late-secretory; S, secretory; LH, luteinizing hormone; ANP-R, atrial naturetic peptide-receptors; cGMP, cyclic guanosine monophosphate; SUSD2, sushi domain containing 2; PGR, progesterone receptor; SRC-2, steroid receptor coactivator-2.