Fig. 3.

Significant differences in tissue classification based on TPM. Within each cohort, paired t-tests compared grey matter (GM) and white matter (WM) images from pipelines using different TPMs, all using the default DARTEL template. TPMs differentially altered tissue classification in a relatively consistent way across the two cohorts, but choice of TPM impacted classification in deep white and grey matter regions as well as across cortical regions. Slices shown at [-9 -1 9]; display is radiological. TOM8=Template-o-Matic 8, COM = CerebroMatic.