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. 2020 Aug 8;47(6):527–542. doi: 10.1007/s10928-020-09704-1

Table 2.

Population characteristics

	N	Age (years)		Sex	Weight (kg)
		Mean	Range	M:F	Mean	Range
K119^a,b	12	26.0	22–33	8:4	74.9	51–103
K155^a	12	26.4	21–45	8:4	75.9	53.5–101
K169^a	20	24.6	21–34	10:10	67.0	47–91
K257^a,b	16	28.5	22–34	9:7	71.2	57–88
K380^a	16	30.0	22–52	12:4	72.4	55.1–96.3
K194^a	12	25.3	21–34	6:6	73.4	55–109
K345^a	11	27.4	19–36	6:5	70.0	53.1–111
Total	99	26.9	19–52	59:40	71.7	47–111
K292^b	16	32.7	22–49	12:4	73.4	61–92
K342^b	12	29.8	19–50	8:4	74.7	50.0–94.1
K363^b	18	33.7	24–50	7:11	67.9	52.8–88.9
Overall	145	28.6	19–52	86:59	71.7	47–111

^aModel development set

^bValidation set