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. 2020 Nov 9;10(11):117. doi: 10.1038/s41408-020-00382-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Kaplan–Meier survival curves for event-free/progression-free (EFS/PFS) and overall survival (OS) of DH/TH, Alt-DH/TH, and Other (translocation positive + copy gain positive + no alteration patients). Progression-free survival is a combination of EFS from one study and PFS from another. A Progression-free survival (p = 0.013) and overall survival (p = 0.0012) of all Alt-DH/TH (n = 51), DH/TH (n = 21), and Other cases (n = 410) in the combined cohort. B Progression-free survival (EFS/PFS) (p = 0.011) and overall survival (p < 0.001) of Alt-DH/TH cases separated by COO class (ABC-like, n = 15; GCB, n = 25; NA/unclassifiable, n = 8), all DH/TH (n = 21), and all Other cases (n = 410). C Progression-free survival (EFS/PFS) (p = 0.012) and overall survival (p = 0.001) of ABC-like Alt-DH/TH (n = 15), DH/TH (n = 21), and ABC-like Other (n = 151) cases in the combined cohort. p Values listed on each graph were derived from a Log Rank test.