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. 2020 Nov 9;10:19319. doi: 10.1038/s41598-020-76356-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Chronically administered electrically stimulated muscle contractions do not result in muscle hypertrophy but do increase capillary density in the tibialis anterior muscle. (A) Mass of the gastrocnemius muscle plotted against body mass across individual mice in the sham and e-stim groups. (B) Mean capillary density in the gastrocnemius muscle shown separately for sham and e-stim groups. (C) Mass of the tibialis anterior muscle plotted against body mass across individual mice in the sham and e-stim groups. (D) Mean capillary density in the tibialis anterior muscle shown separately for sham and e-stim groups. Standard errors shown; n = 8 per bar. *Indicates e-stim group is significantly different from sham (P < 0.05).