Table 3.

Correlation results (Spearman’s rho coefficients) between similarity indices (Dice coefficient and average Hausdorff distance) and size parameters of the segmented metastases for both 2D and 3D ROIs

Correlation	2D ROI		3D ROI
	DC	HD	DC	HD
ROI manual axial diameter	0.42 (p < 0.001)	-0.04 (p = 0.760)	0.45 (p < 0.001)	0.45 (p < 0.001)
ROI maximum 3D diameter	0.37 (p < 0.001)	-0.12 (p = 0.382)	0.42 (p < 0.001)	0.41 (p = 0.002)
ROI volume/area	0.30 (p < 0.001)	-0.17 (p = 0.209)	0.36 (p < 0.001)	0.30 (p = 0.024)

2D Two dimensional, 3D Three dimensional, DC Dice coefficient, HD Hausdorff distance (average), ROI Region of interest