Table 2.
Association of DKC1 protein expression and the expression of other molecular biomarkers in the Nottingham cohort.
| Parameters | DKC1 nuclear protein expression | Adjusted p value | DKC1 nucleolar protein expression | Adjusted p value | ||||
|---|---|---|---|---|---|---|---|---|
| Number (%) | Mean rank | p value | Number (%) | Mean rank | p value | |||
| Oestrogen receptor | ||||||||
| Negative | 182 (20) | 511.1 | 0.01 | 0.04 | 182 (20) | 569.9 | 3.3 × 10−18 | <0.0001 |
| Positive | 748 (80) | 454.4 | 748 (80) | 440.1 | ||||
| Progesterone receptor | ||||||||
| Negative | 362 (39) | 462.9 | 0.92 | 0.92 | 362 (39) | 509.7 | 4.7 × 10−10 | <0.0001 |
| Positive | 565 (61) | 464.6 | 565 (61) | 434.7 | ||||
| HER2 status | ||||||||
| Negative | 815 (88) | 458.5 | 0.034 | 0.1 | 815 (88) | 455.1 | 0.000003 | <0.0001 |
| Positive | 115 (12) | 514.7 | 115 (12) | 539.4 | ||||
| Triple negative status | ||||||||
| Non-triple negative | 789 (85) | 458.5 | 0.058 | 0.12 | 789 (85) | 446.7 | 5.4 × 10−14 | <0.0001 |
| Triple negative | 141 (15) | 504.6 | 141 (15) | 570.9 | ||||
P values in bold means statistically significant.