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. 2020 Nov 9;10:19381. doi: 10.1038/s41598-020-76355-0

Table 2.

Size of inhibition zone and their corresponding statistical significance (p value) of E. coli (a), K. pneumoniae (b) and, S. sonnei (c). Zone size is expressed as mean ± standard deviation in millimeter (mm).

Antibiotic Adjuvant Zone size of inhibition p value
Antibiotic Antibiotic and adjuvant
a) Escherichia coli
Amikacin Zinc Pyrithione 7 ± 0.05 24 ± 1.32 < 0.01
Vitamin D 7 ± 0.05 22 ± 1.53 < 0.01
Vitamin E 7 ± 0.05 23 ± 0.57 < 0.01
Vitamin K 7 ± 0.05 21 ± 0.50 < 0.01
Gentamicin Zinc Pyrithione 6 ± 0.00 22 ± 1.52 < 0.01
Vitamin D 6.4 ± 0.26 20 ± 1.52 < 0.01
Vitamin E 7 ± 0.05 21 ± 0.50 < 0.01
Vitamin K 7 ± 0.05 21 ± 0.58 < 0.01
Kanamycin Zinc Pyrithione 6.2 ± 0.15 22 ± 1.04 < 0.01
Vitamin D 6.9 ± 0.05 27 ± 1.00 < 0.01
Vitamin E 7 ± 0.05 26 ± 0.58 < 0.01
Vitamin K 7 ± 0.05 21 ± 1.00 < 0.01
b) Klebsiella pneumoniae
Amikacin Zinc Pyrithione 7 ± 0.05 17 ± 1.04 < 0.01
Vitamin D 7 ± 0.05 18 ± 0.76 < 0.01
Vitamin E 7 ± 0.05 21 ± 0.50 < 0.01
Vitamin K 7 ± 0.05 15 ± 0.40 < 0.01
Gentamicin Zinc Pyrithione 6.1 ± 0.15 11 ± 0.95 0.02
Vitamin D 7 ± 0.06 18 ± 0.77 < 0.01
Vitamin E 7 ± 0.05 19 ± 1.50 < 0.01
Vitamin K 7 ± 0.05 20 ± 1.32 < 0.01
Kanamycin Zinc Pyrithione 7 ± 0.05 15 ± 1.60 0.01
Vitamin D 7 ± 0.06 18 ± 0.76 < 0.01
Vitamin E 7 ± 0.06 20 ± 1.70 < 0.01
Vitamin K 7 ± 0.06 24 ± 1.25 < 0.01
c) Shigella sonnei
Amikacin Zinc Pyrithione 7 ± 0.05 19 ± 2.00 < 0.01
Vitamin D 7 ± 0.06 20 ± 0.51 < 0.01
Vitamin E 7 ± 0.00 20 ± 1.70 < 0.01
Vitamin K 7 ± 0.05 15 ± 0.55 < 0.01
Gentamicin Zinc Pyrithione 7 ± 0.05 21 ± 2.08 < 0.01
Vitamin D 7 ± 0.05 17 ± 0.64 < 0.01
Vitamin E 7 ± 0.06 17 ± 1.55 < 0.01
Vitamin K 6.5 ± 0.15 15 ± 1.00 < 0.01
Kanamycin Zinc Pyrithione 6.5 ± 0.16 20 ± 0.57 < 0.01
Vitamin D 6.2 ± 0.10 10 ± 0.58 < 0.01
Vitamin E 6 ± 0.00 13 ± 1.00 < 0.01
Vitamin K 6 ± 0.16 08 ± 1.15 0.05