Fig. 3.

Genomic load categories and risks of four clinically more severe outcomes among HFMD cases by enterovirus serotype. (a) EV-A71. (b) CV-A6.

The point indicated risks of clinically more severe outcomes and the line indicated the 95% confidence interval. The one and two red stars indicated p values less than 0.05 and 0.01, respectively, using Cochran-Armitage Trend Test. Genomic load categories of EV-A71 were classified based on Ct values as follows: low, ≥34.4; medium, 28.3–34.3; and high, <28.3. Genomic load categories of CV-A6 were classified based on Ct values as follows: low,≥31.2; medium, 26.7–31.1; and high, <26.7.