Table 3.

Spearman correlation between HERV-P, HERV-H, and HERV-K env gene geometric mean transcription levels; HERV-K pol gene geometric mean transcription levels; and HERV-P, HERV-H, and HERV-K LTR methylation levels in surgical specimens (tumor tissue vs. normal tissue in negative resection margins) collected from a cohort of patients with colon cancer.

	Normal tissuea			Cancer tissue
	Met HERV-P	Met HERV-H	Met HERV-K	Met HERV-P	Met HERV-H	Met HERV-K
rqExpr HERV-P env	−0.22	−0.22	−0.11	0.40	−0.07	−0.15
P-value	0.15	0.13	0.45	0.01	0.68	0.33
Observations (n)	45	49	50	38	39	43
rqExpr_HERV-H env	0.07	0.26	−0.16	0.05	−0.11	0.16
P-value	0.63	0.07	0.27	0.78	0.50	0.31
Observations (n)	46	49	52	38	39	43
rqExpr HERV-K_env	−0.16	−0.17	−0.23	0.33	−0.03	0.29
P-value	0.27	0.24	0.10	0.04	0.88	0.06
Observations (n)	46	49	52	38	39	43
rqExpr HERV-K_pol	−0.11	−0.03	−0.32	0.23	−0.02	−0.03
P-value	0.50	0.87	0.04	0.19	0.92	0.85
Observations (n)	37	39	41	34	35	39

^aNormal tissue collected from negative surgical margins.