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Current phenotype vs. simplified phenotype classification for SM in test cohort.
| Test Cohort | Current genotype classification |
Simplified classification |
||||
|---|---|---|---|---|---|---|
| UM/EM N = 135 |
IM N = 8 |
PM N = 18 |
wt/wt N = 68 |
wt/v N = 54 |
v/v N = 39 |
|
| Slow metabolizer (NDMT/EDF > 35) N = 44 |
23/135 (17%) | 6/8 (75%) | 15/18 (83%) | 3/68 (4%) | 11/54 (20%) | 30/39 (77%) |
| Sensitivity | 44% | |||||
| Specificity | 96% | |||||
| Sensitivity | 81% | |||||
| Specificity | 83% | |||||
