Figure 5.

ACOT11 knock down inhibit tumor growth in vivo. In vivo tumorgenicity was measured by subcutaneously injecting GFP-expressing ACOT11 RNAi lentivirus or control lentivirus transfected A549 into nude mice, n=10. Luciferase fluorescence signaling of xenografts was imaged (A) before mice were sacrificed and the signal intensity within the interested region was quantified (B). Gross pictures of Tumors and corresponding mice was shown (C). Tumor size were monitored (D) at indicated time and tumor weight (E) were measured after mice was sacrificed. Data are presented as mean ± SD. Student t-test was conducted to **P<0.01; ***P<0.001.