Table 1. Clinical characteristics of the study population (n=119).
Characteristics | Number | Percentage (%) |
---|---|---|
Gender | ||
Male | 83 | 69.75 |
Female | 36 | 30.25 |
Age (years) | ||
≤60 | 78 | 65.55 |
>60 | 41 | 34.45 |
Smoking status | ||
No | 59 | 49.58 |
Yes | 60 | 50.42 |
Histology | ||
Adenocarcinoma | 107 | 89.92 |
Non-adenocarcinoma | 12 | 10.08 |
ECOG PS | ||
0–1 | 97 | 81.51 |
≥2 | 22 | 18.49 |
Clinical stage | ||
IIIB | 11 | 9.24 |
IV | 108 | 90.76 |
Brain metastases before treatment | ||
No | 87 | 73.11 |
Yes | 32 | 26.89 |
Bone metastases before treatment | ||
No | 73 | 61.34 |
Yes | 46 | 38.66 |
EGFR exon 20 insert mutant group | ||
A767_V769dupASV | 33 | 27.73 |
S768_D770dupSVD | 19 | 15.97 |
N771_H773dupNPH | 11 | 9.24 |
A763_Y764insFQEA | 2 | 1.68 |
Others | 54 | 45.38 |
EGFR-TKI | ||
No | 108 | 90.76 |
Yes | 11 | 9.24 |
First-line chemotherapy | ||
Pemetrexed-based | 77 | 64.71 |
Non-pemetrexed | 42 | |
Second-line chemotherapy | ||
Pemetrexed-based | 16 | 13.45 |
Non-pemetrexed based | 103 | 86.55 |
EGFR, epidermal growth factor receptor; TKI, tyrosine kinase inhibitor.