TABLE 3.

DNA methylation by adenine or cytosine MTases followed by restriction challenge of the methylated phage SP8 DNA.

Type of DNA MTase	Sequence modified	REase used to challenge DNA	Modification status	Cleavage of gDNA prior to modification
6mA MTase
M. TaqI	TCGA	TaqI	Very Partial	Complete (TaqI)
M.Dam	GATC	MboI	Partial	Complete (MboI)
M.EcoGII	A	MboI	Partial	Complete (MboI)
5mC MTase
M. HaeIII	GGCC	HaeIII	Complete	Complete
M. MspI	CCGG	MspI	Complete	Complete
M. HhaI	GCGC	HhaI	Complete	Complete
M. AluI	AGCT	AluI	Complete	Complete
CpG	CG	HpaII	Complete	Complete
M. HpaII	CCGG	HpaII	Complete	Complete
GpC	GC	HhaI	Complete	Complete