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. 2020 Aug 27;82(10):1492–1496. doi: 10.1292/jvms.20-0049

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©2020 The Japanese Society of Veterinary Science

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)

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Fig. 3. — Gross findings of the liver at necropsy. (A) Marked enlargement of the liver and many white to dark reddish nodules (arrows) on the liver are seen. (B) The lesions are characterized by multifocal pyogranuloma (arrows) and necrotizing granuloma with hemorrhage and fibrinous materials (arrowheads), especially near the central vein (CV). Hematoxylin and eosin (HE) stain. Bar=200 µm. (C) Immunohistochemical image of the lesion same as B. Scattered viral antigens (stained red-brown) are observed in the pyogranuloma (arrows) and around the necrotizing granuloma (arrowheads). Bar=200 µm.