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. 2020 Oct 14;17(171):20200693. doi: 10.1098/rsif.2020.0693

Table 1.

Definition of the model attractors and related phenotypes. References supporting the definitions are listed.

model state considered phenotype references
active: miR-190, miR-34, miR-340, miR-1199, miR-129, miR-200, CDH1 (highest level), GRHL2, ESRP1 epithelial [813,21,31,35]
inactive: TGFB, SNAIL1, TWIST1, ZEB1, CD44s, HAS2, HA, VIM
active: miR-190, miR-340, miR-1199, miR-129, miR-200, CDH1 (intermediate level), GRHL2, ESRP1, VIM (intermediate level), SNAIL1 (high level) hybrid [813,21,31,35]
inactive: miR-34, TGFB, TWIST1, ZEB1, CD44s, HAS2, HA
active: miR-190, miR-340, miR-1199, TWIST1, miR-200, CDH1 (intermediate level), GRHL2, ESRP1, VIM (intermediate level), SNAIL1 (high level) hybrid [813,21,31,35]
inactive: miR-34, TGFB, miR-129, ZEB1, CD44s, HAS2, HA
active: TGFB, ZEB1 (high/highest levels), CD44s, HAS2, HA, TWIST1, VIM (highest level), SNAIL1 (high/highest levels) mesenchymal [813,21,31,35]
inactive: miR-34, miR-190, miR-340, miR-1199, miR-200, CDH1, GRHL2, ESRP1, miR-129