表2.
A-EGJOO与F-EGJOO组食管动力参数的比较
Comparison of esophageal motility metrics between A-EGJOO and F-EGJOO patients
| Items | Control (c), n=27 | A-EGJOO (a), n=42 | F-EGJOO (f), n=69 | P value |
| EGJOO, esophagogastric junction outlet obstruction; A-EGJOO, anatomic EGJOO; F-EGJOO, functional EGJOO; LES, low esophageal sphincter; IRP4s, integrated relaxation pressure for four seconds; DCI, distal contractile integral; UES, upper esophageal sphincter. Data are presented as x±s or M (P25, P75). | ||||
| Age/years | 46.26±13.29 | 57.12±13.54 | 52.42±12.96 | P=0.08 (c/a: P=0.003; a/f: P=0.033) |
| Gender (Male :Female) | 11 :16 | 18 :24 | 16 :53 | a/f: P=0.034 |
| Main symptoms, n | ||||
| Dysphagia | 0 | 17 | 16 | a/c: P < 0.001; f/c: P=0.005 |
| Chest pain/discomfort | 0 | 14 | 20 | a/c: P < 0.001 |
| Heartburn/acid regurgitation | 0 | 10 | 20 | a/c: P=0.005; f/c: P=0.001 |
| Belching | 0 | 0 | 2 | |
| Pharyngeal foreign body sensation | 0 | 0 | 4 | |
| Abdominal pain | 0 | 0 | 2 | |
| Others | 0 | 1 | 5 | |
| LES rest pressure/mmHg | 20.10 (16.10, 23.50) | 29.95 (27.40, 39.25) | 31.20 (26.30, 37.50) | P < 0.001 (c/a: P < 0.001; c/f: P < 0.001) |
| IRP4s/mmHg | 6.80 (5.80, 10.60) | 17.65 (16.03, 20.98) | 17.40 (16.30, 19.80) | P < 0.001 (c/a: P < 0.001; c/f: P < 0.001) |
| Distal esophageal peristalsis amplitude/mmHg | 71.90 (52.90, 91.55) | 82.35 (61.43, 120.25) | 79.70 (54.80, 113.00) | |
| Distal esophageal peristalsis duration/s | 2.90 (2.70, 3.15) | 3.30 (2.90, 3.85) | 3.30 (2.90, 3.50) | P=0.007 (c/a: P=0.002; c/f: P=0.031) |
| Peristalsis amplitude 3 cm above LES/mmHg | 71.30 (54.90, 108.85) | 96.25 (65.48, 133.20) | 88.00 (57.10, 120.10) | |
| Peristalsis amplitude 7 cm above LES/mmHg | 63.70 (50.65, 81.35) | 77.55 (53.40, 99.65) | 67.00 (42.10, 97.60) | |
| Peristalsis amplitude 11 cm above LES/mmHg | 50.50 (43.90, 66.45) | 64.20 (49.23, 83.18) | 62.50 (44.30, 83.90) | |
| Average DCI/(mmHg·s·cm) | 1 183.30 (807.65, 1 518.85) | 1 393.85 (970.33, 2 304.13) | 1 343.80 (705.00, 1 941.00) | |
| Maximum DCI/(mmHg·s·cm) | 1 852.50 (1 274.80, 2 317.75) | 2 262.35 (1 387.98, 3 286.05) | 1 860.80 (1 279.60, 2 430.30) | |
| UES rest pressure/mmHg | 80.90 (49.20, 101.70) | 57.00 (36.33, 73.43) | 60.70 (39.60, 84.50) | |
| Distal latency/s | 6.30 (5.50, 8.15) | 5.80 (5.20, 6.48) | 6.20 (5.50, 7.30) | |
| Intra bolus pressure/mmHg | 4.60 (3.50, 7.00) | 6.80 (5.20, 9.20) | 5.10 (3.10, 7.60) | P=0.014 (c/a: P=0.009; a/f: P=0.016) |