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. 2020 Jun 3;52(5):809–814. [Article in Chinese] doi: 10.19723/j.issn.1671-167X.2020.05.003

表2.

806个中国NSCL/P核心家系传递不平衡检验结果

The selected single SNP and haplotype association results with nominal significance based on TDT in 806 Chinese case-parents trios

Type Gene Haplotype SNP ID P value
SNP, single nucleotide polymorphism; TDT, transmission disequilibrium test.
SNP PTCH1 - rs4448343 0.023
Haplotype PTCH1 AG rs10512249-rs4448343 0.025
Haplotype SHH GC rs1461208-rs7786445 0.026
Haplotype PTCH1 GA rs10512249-rs4448343 0.031
Haplotype PTCH1 CGA rs16909865-rs10512249-rs4448343 0.036
Haplotype SHH GCG rs1461208-rs7786445-rs12698335 0.036
Haplotype SHH GGC rs288756-rs288758-rs1151790 0.047