表3.
806个中国NSCL/P核心家系PoO效应结果
The results of PoO effects in 806 Chinese case-parents trios
| Gene | SNP ID |
RRm
(95% CI) |
RRm P value |
RRf (95% CI) |
RRf P value |
RRR (95% CI) |
RRR P value |
| SNP, single nucleotide polymorphism; TDT, transmission disequilibrium test; RRR, ratio of relative risks; PoO, parent-of-origin effects. | |||||||
| SHH | rs288765-rs1233563 | 0.43 (0.15－1.29) |
0.134 | 1.04 (0.41－2.75) |
0.919 | 0.41 (0.20－0.86) |
0.018 |
| SHH | rs12537550-rs11765352 | 1.22 (0.87－1.71) |
0.239 | 0.90 (0.64－0.24) |
0.518 | 1.36 (1.01－1.82) |
0.036 |
| SHH | rs872723-rs288765-rs1233563 | 0.54 (0.23－1.29) |
0.161 | 1.33 (0.66－2.69) |
0.427 | 0.41 (0.20－0.86) |
0.017 |
| SHH | rs288765-rs1233563-rs288756 | 0.58 (0.28－1.20) |
0.153 | 1.29 (0.72－2.31) |
0.386 | 0.45 (0.21－0.95) |
0.035 |
| SHH | rs6459952-rs12537550-rs11765352 | 1.16 (0.84－1.61) |
0.366 | 0.81 (0.59－1.11) |
0.192 | 1.44 (1.06－1.95) |
0.021 |
| SHH | rs12537550-rs11765352-rs6971211 | 1.13 (0.83－1.56) |
0.433 | 0.81 (0.59－1.11) |
0.180 | 1.40 (1.04－1.90) |
0.025 |