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High glucose affected oxidative and antioxidative activities in HUVECs. A-C. LY333531 rescued the decreased activities of CAT, SOD, and GSH-Px in HUVECs treated with glucose. D. LY333531 rescued the glucose-induced increase in the MDA content in HUVECs. Each group was a mixture of cells collected three times (n = 3), and the experiment was repeated three times. Values are the means and standard errors (*P<0.05 and **P<0.01 versus CON).
