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. 2020 Oct 15;12(10):6811–6826.

Figure 7.

Figure 7

Effect of exosomes isolated from SMMC-7721 cells on tumor formation in nude mice combined with hsa-miR-24-3p knockdown in the exosomes of EMT SMMC-7721 cells. A. Effect of different treatments on the weight of nude mice. B. Effect of different treatments on subcutaneous tumor formation volume. *; P < 0.05 (vs. SMMC-7721 cells); #; P < 0.05 (vs. exosomes of EMT SMMC-7721 cells). C. Phenotype and weight of different treatments on subcutaneous tumors. **; P < 0.01, ****; P < 0.0001 (vs. SMMC-7721 cells), ####; P < 0.0001 (vs. exosomes of EMT SMMC-7721 cells). D. qPCR analysis of hsa-miR-24-3p expression following different treatments in tumors. **; P < 0.01, ****; P < 0.0001 (vs. SMMC-7721 cells), ####; P < 0.0001 (vs. exosomes of EMT SMMC-7721 cells). E. WB analysis of E-cadherin, N-cadherin, vimentin, and β-catenin expression following different treatments in tumors. Control, SMMC-7721 cells; EXO, SMMC-7721 cells treated with exosomes of SMMC-7721 cells; EMT EXO, SMMC-7721 cells treated with exosomes of EMT SMMC-7721 cells; [EMT EXO (miR-24-3p In)], SMMC-7721 cells treated with EMT SMMC-7721 exosomes with hsa-miR-24-3p knockdown.