Table 2.

Risk factors for NAFLD according to the Cox regression analyses

Variable	Univariate analysis		Multivariate analysis
	OR (95% CI)	P value	OR (95% CI)	P value
Age (years)	1.596 [1.493, 1.706]	<0.001	1.276 [1.182, 1.378]	<0.001
Sex (Male vs. Female)	3.610 [3.166, 4.115]	<0.001	1.718 [1.416, 2.084]	<0.001
Hypertension (Without vs. With)	2.164 [1.897, 2.470]	<0.001	1.090 [0.940, 1.264]	0.193
BMI (kg/m2)	1.616 [1.560, 1.674]	<0.001	1.417 [1.364, 1.473]	<0.001
FBG (mmol/l)	1.362 [1.305, 1.421]	<0.001	1.115 [1.047, 1.188]	0.001
TC (mmol/l)	1.387 [1.270, 1.514]	<0.001	1.204 [1.085, 1.337]	0.001
TG (mmol/l)	1.435 [1.401, 1.471]	<0.001	1.193 [1.143, 1.245]	<0.001
LDL-c (mmol/l)	1.909 [1.669, 2.184]	<0.001	0.909 [0.691, 1.195]	0.714
HDL-c (mmol/l)	0.183 [0.149, 0.224]	<0.001	0.533 [0.420, 0.677]	<0.001
Cr (mmol/l)	1.003 [1.003, 1.004]	<0.001	0.990 [0.985, 1.001]	0.051
BUN (mmol/l)	1.097 [1.060, 1.135]	<0.001	0.948 [0.898, 1.000]	0.053
UA (mmol/l)	1.007 [1.006, 1.008]	<0.001	1.003 [1.002, 1.004]	<0.001
ALT (U/L)	1.008 [1.007, 1.009]	<0.001	1.017 [1.011, 1.023]	<0.001
AST (U/L)	1.007 [1.005, 1.009]	<0.001	0.978 [0.966, 1.001]	0.058
GGT (U/L)	1.009 [1.008, 1.010]	<0.001	1.002 [1.000, 1.004]	0.069
TBil (μmol/l)	0.999 [0.988, 1.011]	0.910	-	-
DBil (μmol/l)	0.940 [0.853, 1.037]	0.216	-	-

Data are shown as odds ratio (95% CI), P value. NAFLD, nonalcoholic fatty liver disease; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting plasma glucose; TC, total cholesterol; TG, triglyceride; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; BUN, blood urea nitrogen; Cr, creatinine; UA, uric acid; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; TBil, total bilirubin; DBil, direct bilirubin.