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Metformin enhanced the vascular density and the expression of CD31 in hyperoxic lung injury on P7 and P14. A. Immunohistochemistry staining showed that metformin enhanced the vascular density on P7 and P14; B. Quantitative analysis of the percentage of microvascular density by manual counting on P7 and P14. magnification: 400×, scale bar: 20 μm. All images were acquired under the same condition and displayed at the same scale (Data represent the mean ± SD. *P<0.05, **P<0.01).
