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. 2020 Nov 9;18:165. doi: 10.1186/s12915-020-00899-w

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Chromosomal FISH of telomere repeats. Both panels show chromosomal fluorescent in situ hybridisation using probes against the canonical telomere sequence (TTAGGGx7). a In haploid spermatozoa, only one focus is visible for each of the six chromosomes (arrows), whereas two foci per chromosome (= 12) would be expected if telomeric repeats were present on both ends. b A metaphase figure shows chromatids joined at their centromeric ends, which lack probe signal, whereas probe is visible at the opposing ends of each sister chromatid (arrows)