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. 2020 Nov 9;21:294. doi: 10.1186/s12931-020-01554-2

Table 2.

Subgroup analyses of the association between vitamin D and OSA in this meta-analysis

Subgroup No. of studies Sample Mean difference (95% CI) P for Heterogeneity I-squared Value P Value between groups
Experiment Control
Ethnic
 Caucasian 16 3547 1707 − 0.59[− 0.9, − 0.27] 0.0003 93% P < 0.00001
 Asian 10 662 382 − 1.28[− 1.92, − 0.64] P < 0.0001 94% P < 0.00001
BMI
 Normal range 3 176 129 − 1.66[− 2.73, − 0.59] 0.002 93% P < 0.00001
 Overweight 4 1983 1186 − 1.33[− 2.55, − 0.1] 0.03 98% P < 0.00001
 Obesity 17 1981 634 − 0.57[− 0.93, − 0.21] 0.002 92% P < 0.00001
PSG degree
 I 19 3750 1833 − 0.55[− 0.85, − 0.26] 0.0002 93% P < 0.00001
 II 4 277 157 − 1.4[− 2.21, − 0.58] 0.0008 91% P < 0.00001
 III 3 182 99 − 1.93[− 2.28, − 1.58] P < 0.00001 21% 0.28
Study quality
 High/A 18 3640 1769 − 0.61[− 0.92, − 0.31] P < 0.0001 93% P < 0.00001
 Medium/B 8 569 320 − 1.37[− 2.07, − 0.66] 0.0001 95% P < 0.00001
Study latitude
 Low latitude 4 336 117 − 1.24[− 2.25, − 0.23] 0.02 94% P < 0.00001
 Middle latitude 22 3873 1972 − 0.8[− 1.11, − 0.49] P < 0.00001 95% P < 0.00001

OSA Obstructive sleep apnea, BMI body mass index, PSG polysomnogram